Xanomeline Low Dose 
 (n = 84)	Xanomeline High Dose 
 (n = 84)	Placebo 
 (n = 86)	
Age (Year)				
	n (missing)	84 (0)	84 (0)	86 (0)	
	Mean (SD)	75.7 (75.67)	74.4 (74.38)	75.2 (75.21)	
	Median (Q1, Q3)	77.5 (71.0, 82.0)	76.0 (70.8, 80.0)	76.0 (69.3, 81.8)	
	Min, Max	51, 88	56, 88	52, 89	
Pooled Age Group, n (%)				
	<65	8 ( 9.5)	11 (13.1)	14 (16.3)	
	65-80	47 (56.0)	55 (65.5)	42 (48.8)	
	>80	29 (34.5)	18 (21.4)	30 (34.9)	
Race, n (%)				
	ASIAN	0	0	0	
	WHITE	78 (92.9)	74 (88.1)	78 (90.7)	
	BLACK OR AFRICAN AMERICAN	6 ( 7.1)	9 (10.7)	8 ( 9.3)	
	AMERICAN INDIAN OR ALASKA NATIVE	0	1 ( 1.2)	0	
Baseline Height (cm)				
	n (missing)	84 (0)	84 (0)	86 (0)	
	Mean (SD)	163.43 (163.433)	165.82 (165.820)	162.57 (162.573)	
	Median (Q1, Q3)	162.60 (157.50, 170.20)	165.10 (157.50, 172.77)	162.60 (154.00, 171.18)	
	Min, Max	135.9, 195.6	146.1, 190.5	137.2, 185.4	
Baseline Weight (kg)				
	n (missing)	84 (1)	84 (0)	86 (0)	
	Mean (SD)	67.28 (67.280)	70.00 (70.005)	62.76 (62.759)	
	Median (Q1, Q3)	64.90 (56.05, 77.45)	69.20 (56.98, 80.30)	60.55 (53.63, 74.18)	
	Min, Max	45.4, 106.1	41.7, 108	34, 86.2	
Baseline BMI (kg/m^2)				
	n (missing)	84 (1)	84 (0)	86 (0)	
	Mean (SD)	25.06 (25.063)	25.35 (25.348)	23.64 (23.636)	
	Median (Q1, Q3)	24.30 (22.15, 27.80)	24.80 (22.70, 27.85)	23.40 (21.20, 25.60)	
	Min, Max	17.7, 40.1	13.7, 34.5	15.1, 33.3